Due to its high accuracy and fast, simple workflow, capillary electrophoresis (CE) is a foundational technology for clinical applications. CE is an invaluable tool used to detect genetic variations ...

Due to its high accuracy and fast, simple workflow, capillary electrophoresis (CE) is a foundational technology for clinical applications. CE is an invaluable tool used to detect genetic variations ...

In 1997, Sanger, Nicklen and Coulson described a method for determining DNA nucleotide sequences. 1 Nearly five decades later, Sanger sequencing remains an entrenched technology for targeted ...

Without a doubt, the quarter-century-old Sanger sequencing method performed like a champ during the Human Genome Project. But with the capacity to read only a few hundred bases per reaction, it is far ...

In a way, sequencing DNA is very simple: There's a molecule, you look at it, and you write down what you find. You'd think it would be easy—and, for any one letter in the sequence, it is. The problem ...