Every time a cell divides, it must copy its entire genome so that each daughter cell inherits a complete set of DNA. During ...

For almost 60 years, scientists have tried to understand why DNA doesn't replicate wildly and uncontrollably every time a ...

Researchers have identified an alternate method to study changes during the DNA replication process in lab settings using genetically modified yeast. The new approach offers a clearer window than ...

For almost 60 years, scientists have tried to understand why DNA doesn't replicate wildly and uncontrollably every time a cell divides – which they need to do constantly. Without this process, we ...

DNA replication is a fundamental process essential for bacterial growth and survival. Initiation begins at the chromosomal origin (oriC), where the conserved initiator protein DnaA assembles into an ...

A protein that is involved in determining which enzymes cut or unwind DNA during the replication process has been identified. A protein that is involved in determining which enzymes cut or unwind DNA ...

A protein that is involved in determining which enzymes cut or unwind DNA during the replication process has been identified in a new study. In a new paper published in Nature Communications, an ...

DNA replication is a complex process with many moving parts. In baker's yeast, the molecular complex Ctf18-RFC keeps parts of the replication machinery from falling off the DNA strand. Human cells use ...

Notably, inhibition of cGAS-STING from early development rescued mice from developmental lethality and premature aging caused ...

In a way, sequencing DNA is very simple: There's a molecule, you look at it, and you write down what you find. You'd think it would be easy—and, for any one letter in the sequence, it is. The problem ...